Molecular formula: C₅H₆Br₃N (or [PyH]Br₃, where Py represents the pyridine ring)
Molecular weight: 319.82
CAS No.: 39416-48-3
Appearance: Dark red crystalline solid

Applications

Organic Bromination Reactions

• • α-Bromination of Ketones:

    • Highly selective bromination of steroidal ketones (equatorial substitution in acetic acid solvent; axial substitution in carbon tetrachloride).

    • Solvent-controlled stereochemistry of cyclohexanone bromination products.

  • Controlled Bromination of Aromatic Rings:

    • Selective monobromination of aniline to produce ortho-bromoaniline (75–95% yield).

    • Tunable mono-, di-, or tribromination of 2-hydroxy-4-methoxybenzaldehyde by adjusting PTB equivalents.

  • Dehydrogenation/Oxidation Transformations:

    • Conversion of ketones to phenols (e.g., in steroidal compounds).

    • Alcohols → alkyl bromides; thioacetals → aldehydes/ketones (under phase-transfer conditions).

• Emerging Applications

  • • Pharmaceutical Synthesis: Preparation of intermediates for steroidal drugs such as trestolone.

    • Metal Ion Adsorption: Captures heavy metal ions (e.g., lead, copper) in aqueous solutions.