CAS Number: 1778-09-2
Molecular Formula: C9H10OS
Molecular Weight: 166.24
EINECS Number: 217-213-1 

4-Methylthiobenzophenone (CAS number: 1778-09-2) is an important pharmaceutical intermediate. Its main applications are as follows: 
Synthesis of Anti-Joint炎 Drugs
As a key intermediate of the non-steroidal anti-inflammatory drug Rofecoxib, it is used to selectively inhibit the COX-2 enzyme and relieve joint pain and inflammation. 
2. ‌Other pharmaceutical intermediates ‌
‌Etoricoxib intermediate ‌: Through the Willgerodt-Kindler reaction, it can be converted into 4-methylthiobenzoic acid, and further synthesized into the COX-2 inhibitor etoricoxib (Etoricoxib) 
Anti-allergy drugs: May be involved in the synthesis of histamine receptor modulators, but further verification is needed. 
3. Industrial and Research Applications
‌Organic Synthesis‌: As a thioylation reagent, it is used to construct sulfur-containing heterocyclic compounds or aryl sulfides.
‌Flavor Chemistry‌: The derivatives can be used to formulate flavors such as lilac and raspberry.